Animal to Human Transplants

Animal to human transplants: the ethics of xenotransplantation (2).

This article is the concluding part of the discussion of ethical issues around xenotransplantation which was commenced in the May issue of the journal. Very little discussion has been published in the professional press on this topic. The message of the articles is that it behoves us to think about these issues before commencing such a new course.

Neuro-immune interactions of neural stem cell transplants: from animal disease models to human trials.

Stem cell technology is a promising branch of regenerative medicine that is aimed at developing new approaches for the treatment of severely debilitating human diseases, including those affecting the central nervous system (CNS). Despite the increasing understanding of the mechanisms governing their biology, the application of stem cell therapeutics remains challenging. The initial idea that st...

The first baboon-to-human transplants.

Human Renal Transplants

Tissues obtained from 34 human renal allografts by biopsy, 1 to 31 months after transplantation, were studied by histologic, immunofluorescence, and immunoferritin techniques. Our purpose was to gain more precise information concerning the localization of immunoglobulins and complement in glomeruli and to describe the associated tubular and vascular changes. 1. Localization of fluorescein-label...

Human Renal Transplants

I into patients whose immune and 31 months respectively. One of these l,esl,onses have been modified by chronic patients died suddenly from renal infarcIlrnllia, ionizing radiation, various imtion 1 nlonth later, while another slowly lllunosuppressive drugs, or by some comdeteriorated and perished 10 months after ' \,ination of these. In most instances the the onset of proteinuria. The other fo...